NYX Hotels Expands: New Prague Location Opens as Second in Europe

NYX Hotel has opened its second location in Prague, following the brand’s debut in Milan earlier this year. The lifestyle property combines bold design with a raw, artistic aesthetic to create a memorable urban stay.

Situated in the heart of Prague, the hotel occupies a historically preserved building designed in the Czech Rondo-Cubist style. Inside, a contemporary art concept—developed in collaboration with local creators—shapes the public spaces and rooms, offering guests a strong sense of place.

The hotel features 91 rooms ranging from cozy Little Star Rooms to the expansive Godde’s Suite, which includes a private terrace and city views. Each room reflects a distinct color and material palette conceived specifically for the property, pairing custom-made elements with artwork that references Prague’s culture and architecture.

“NYX Prague is a hotel for individualists: art, design, music and nightlife are woven into a single concept that engages all the senses,” said Daniel Roger, managing director of Leonardo Hotels Europe. This approach aligns with the brand’s broader identity, emphasizing creative expression and urban energy.

Local artists were integral to the hotel’s identity, contributing authentic pieces and ideas that shape both the décor and the guest experience. Their contributions help the hotel feel rooted in the city’s creative community rather than simply being a generic boutique property.

With its mix of preserved architectural detail and contemporary artistic interventions, NYX Prague aims to bridge historic charm and modern urban living. The hotel plans ongoing collaborations with Prague’s creatives, positioning itself as a cultural hub and a gathering place for residents and visitors alike.

Guests can expect an experience that prioritizes visual storytelling and a distinct design language across communal areas and guest rooms. By emphasizing locally sourced creative input and carefully curated interiors, NYX Prague offers a lively alternative for travelers seeking style, authenticity and proximity to the city’s attractions.